Barst RJ, Rubin LJ, McGoon MD, Caldwell EJ, Long WA, Levy PS. Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug ReferenceDisclosure: Received salary from Medscape for employment. 369(4):319-29. 2017. 2013 Oct. 82(10):1743-8. 21(3):305-9. Diuretic treatment for the sodium retention of congestive heart failure. Wang B, Feng Y, Jia LQ, et al. [Medline]. Excessive volume depletion can lead to a decline in cardiac output. Diuretics should be used cautiously because small decreases in preload often worsen cor pulmonale. Ali A Sovari, MD, FACP, FACC Attending Physician, Cardiac Electrophysiologist, Cedars Sinai Medical Center and St John's Regional Medical Center Diuretics. Kim WJ, Yim JJ, Kim DK, et al. As there was diuretics … Shih WJ, Kousa K, Mitchell B, Huang WS. Han MK, McLaughlin VV, Criner GJ, Martinez FJ. [Medline]. Often found ordering diuretics in the Cardiothoracic Surgery ICU or posting cat photos on twitter. 2014 Apr 10. 12:3415-23. [Medline]. 2014 Nov 11. Diuretics are given to decrease excess fluid that collects in a part of your body, such as your legs. Pharmacotherapeutic management of pulmonary arterial hypertension. Abraham G Kocheril, MD, FACC, FACP, FHRS is a member of the following medical societies: American College of Cardiology, Central Society for Clinical and Translational Research, Heart Failure Society of America, Cardiac Electrophysiology Society, American College of Physicians, American Heart Association, American Medical Association, Illinois State Medical SocietyDisclosure: Nothing to disclose. Am J Cardiol. 2006 Nov. 28(5):999-1004. N Engl J Med. Please confirm that you would like to log out of Medscape. 5(2):133-48. Pulmonary vasodilators (eg, hydralazine, calcium channel blockers, nitrous oxide, prostacyclin, phosphodiesterase inhibitors), … [Medline]. Galie N, Ghofrani HA, Torbicki A, et al. Konstantinides S, Torbicki A. If you log out, you will be required to enter your username and password the next time you visit. Eur Rev Med Pharmacol Sci. 18(3):148-62. Curr Cardiol Rev. 345(20):1465-72. Minerva Pediatr. Meyer G, Vicaut E, Danays T, et al, for the PEITHO Investigators. … Hoeper MM. Another potential complication of diuresis is the production of a hypokalemic metabolic alkalosis, which diminishes the effectiveness of carbon dioxide stimulation on the respiratory centers and lessens ventilatory drive. 2005 Nov 1. [Medline]. Chron Respir Dis. [Current acquisitions in diuresis and diuretic therapy]. Pulmonary vasodilators (eg, hydralazine , calcium channel blockers, nitrous oxide, prostacyclin, … Diuretics are the mainstay of therapy for pulmonary hypertension due to left-sided heart disease (PH-LHD). 2005. [Medline]. [Medline]. 10(3):153-62. [Full Text]. Theophylline improves global cardiac function and reduces dyspnea in chronic obstructive lung disease. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. [Medline]. Ann Intern Med. J Am Coll Cardiol. Lungu A, Wild JM, Capener D, Kiely DG, Swift AJ, Hose DR. MRI model-based non-invasive differential diagnosis in pulmonary hypertension. Common causes of cor pulmonale include: 1. This article is directed primarily to primary care physicians. Patients presenting with cor pulmonale should be assessed for the need for long-term oxygen therapy. The goal of diuretics is to alleviate volume overload and to lower both right- and left-sided filling pressures. 10(4):e41-2. 2014 Feb. 30(2):315-20. N Engl J Med. 13(2):294-6. [Medline]. Curr Opin Crit Care. How does ARDS affect the right ventricle? We report on a 53-year-old male patient who presented with severe dyspnea at rest and massive volume overload because of decompensated cor pulmonale. Primary pulmonary hypertension: natural history and the importance of thrombosis. [Medline]. Theophylline in chronic obstructive pulmonary disease: new horizons. [Indication, selection, dosage and pro's and con's for use of diuretics in chronic congestive heart failure]. Sastry BK, Narasimhan C, Reddy NK, Raju BS. J Am Coll Cardiol. [Medline]. However, removing larger volumes of fluid without causing electrolyte abnormalities generally requires a more sophisticated diuretic … 126(1 Suppl):35S-62S. Gorcsan J 3rd, Tanaka H. Echocardiographic assessment of myocardial strain. [Medline]. Drugs. 111(23):3105-11. Clinical efficacy of sildenafil in primary pulmonary hypertension: a randomized, placebo-controlled, double-blind, crossover study. 43(7):1149-53. Oxygen therapy, diuretics, vasodilators, digitalis, theophylline, and anticoagulation therapy are all different modalities used in the long-term management of chronic Cor Pulmonale. [Medline]. Ghofrani HA, D'Armini AM, Grimminger F, et al, for the CHEST-1 Study Group. Severe COPD cases from Korea, Poland, and USA have substantial differences in respiratory symptoms and other respiratory illnesses. Volume overload due to cor pulmonale with systemic congestion. 2009 Aug. 93(2):135-40. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly93d3cubWVkc2NhcGUuY29tL2Fuc3dlcnMvMTU0MDYyLTY5MjEzL3doYXQtaXMtdGhlLXJvbGUtb2YtZGl1cmV0aWNzLWluLXRoZS10cmVhdG1lbnQtb2YtY29yLXB1bG1vbmFsZQ==. Adcirca prescribing information. Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension. Incident diuretic use, particularly use of loop diuretics, may increase the risk for respiratory-related morbidity and mortality in older adults with nonpalliative chronic obstructive … Int J Chron Obstruct Pulmon Dis. J Magn Reson Imaging. About Cor Pulmonale Failure of the right side of the heart caused by prolonged high blood pressure in the pulmonary artery and right ventricle of the heart. Sildenafil citrate therapy for pulmonary arterial hypertension. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/, NLM Diuretics are used in the management of chronic cor pulmonale, particularly when the RV filling volume is markedly elevated and in the management of associated peripheral edema. Fine-Goulden MR, Manna S, Durward A. Cor pulmonale due to congenital central hypoventilation syndrome presenting in adolescence. Treatment mainly consists of management of the underlying causes of PH and cor pulmonale. Eur J Radiol. Abraham G Kocheril, MD, FACC, FACP, FHRS Professor of Medicine, University of Illinois College of Medicine Risk factors associated with chronic obstructive pulmonary disease early readmission. Acute cor pulmonale … Calcium channel blockers are pulmonary artery vasodilators that … Central Society for Clinical and Translational Research, Society for Cardiovascular Magnetic Resonance. The following are not recommended for the treatment of cor pulmonale: angiotensin-converting enzyme inhibitors, calcium-channel blockers, alpha-blockers or digoxin (unless there is atrial fibrillation)[2]. 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